Michael Tscherpel

A. Niess, M. Loeffler, J. D. Simen, and R. Takors, “Repetitive Short-Term Stimuli Imposed in Poor Mixing Zones Induce Long-Term Adaptation of E-coli Cultures in Large-Scale Bioreactors: Experimental Evidence and Mathematical Model,” FRONTIERS IN MICROBIOLOGY, vol. 8, doi: 10.3389/fmicb.2017.01195.

J. D. Simen et al., “Transcriptional response of Escherichia coli to ammonia and glucose fluctuations,” MICROBIAL BIOTECHNOLOGY, vol. 10, Art. no. 4, SI, doi: 10.1111/1751-7915.12713.

A. Niess, J. Failmezger, M. Kuschel, M. Siemann-Herzberg, and R. Takors, “Experimentally Validated Model Enables Debottlenecking of in Vitro Protein Synthesis and Identifies a Control Shift under in Vivo Conditions,” ACS SYNTHETIC BIOLOGY, vol. 6, Art. no. 10, doi: 10.1021/acssynbio.7b00117.

J. Lange, F. Mueller, K. Bernecker, N. Dahmen, R. Takors, and B. Blombach, “Valorization of pyrolysis water: a biorefinery side stream, for 1,2-propanediol production with engineered Corynebacterium glutamicum,” BIOTECHNOLOGY FOR BIOFUELS, vol. 10, doi: 10.1186/s13068-017-0969-8.

J. Failmezger, M. Rauter, R. Nitschel, M. Kraml, and M. Siemann-Herzberg, “Cell-free protein synthesis from non-growing, stressed Escherichia coli,” SCIENTIFIC REPORTS, vol. 7, doi: 10.1038/s41598-017-16767-7.

A. Teleki, M. Rahnert, O. Bungart, B. Gann, I. Ochrombel, and R. Takors, “Robust identification of metabolic control for microbial L-methionine production following an easy-to-use puristic approach,” METABOLIC ENGINEERING, vol. 41, pp. 159–172, doi: 10.1016/j.ymben.2017.03.008.

M. Krone et al., “Molecular Surface Maps,” IEEE TRANSACTIONS ON VISUALIZATION AND COMPUTER GRAPHICS, vol. 23, Art. no. 1, doi: 10.1109/TVCG.2016.2598824.

J. Failmezger, J. Ludwig, A. Niess, and M. Siemann-Herzberg, “Quantifying ribosome dynamics in Escherichia coli using fluorescence,” FEMS MICROBIOLOGY LETTERS, vol. 364, Art. no. 6, doi: 10.1093/femsle/fnx055.

M. Loeffler et al., “Switching between nitrogen and glucose limitation: Unraveling transcriptional dynamics in Escherichia coli,” JOURNAL OF BIOTECHNOLOGY, vol. 258, Art. no. SI, doi: 10.1016/j.jbiotec.2017.04.011.

G. Eigenstetter and R. Takors, “Dynamic modeling reveals a three-step response of Saccharomyces cerevisiae to high CO2 levels accompanied by increasing ATP demands,” FEMS YEAST RESEARCH, vol. 17, Art. no. 1, doi: 10.1093/femsyr/fox008.

A. Michalowski, M. Siemann-Herzberg, and R. Takors, “Escherichia coli HGT: Engineered for high glucose throughput even under slowly growing or resting conditions,” METABOLIC ENGINEERING, vol. 40, pp. 93–103, doi: 10.1016/j.ymben.2017.01.005.

J. Lange, R. Takors, and B. Blombach, “Zero-growth bioprocesses: A challenge for microbial production strains and bioprocess engineering,” ENGINEERING IN LIFE SCIENCES, vol. 17, Art. no. 1, doi: 10.1002/elsc.201600108.

S. C. Anenberg et al., “Survey of Ambient Air Pollution Health Risk Assessment Tools,” RISK ANALYSIS, vol. 36, Art. no. 9, SI, doi: 10.1111/risa.12540.

I. T. Alt and B. Plietker, “Iron-Catalyzed Intramolecular C(sp(2))-H Amination,” ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 55, Art. no. 4, doi: 10.1002/anie.201510045.

A. Bardossy and S. Hoerning, “Random Mixing: An Approach to Inverse Modeling for Groundwater Flow and Transport Problems,” TRANSPORT IN POROUS MEDIA, vol. 114, Art. no. 2, SI, doi: 10.1007/s11242-015-0608-4.

I. Amm and D. H. Wolf, “Molecular mass as a determinant for nuclear San1-dependent targeting of misfolded cytosolic proteins to proteasomal degradation,” FEBS LETTERS, vol. 590, Art. no. 12, doi: 10.1002/1873-3468.12213.

F. Beck, S. Koch, and D. Weiskopf, “Visual Analysis and Dissemination of Scientific Literature Collections with SurVis,” IEEE TRANSACTIONS ON VISUALIZATION AND COMPUTER GRAPHICS, vol. 22, Art. no. 1, doi: 10.1109/TVCG.2015.2467757.

S. Aicher, M. Hirsch, and Z. Christian, “Hybrid cross-laminated timber plates with beech wood cross-layers,” CONSTRUCTION AND BUILDING MATERIALS, vol. 124, pp. 1007–1018, doi: 10.1016/j.conbuildmat.2016.08.051.

S. Bagheri, N. Strohfeldt, F. Sterl, A. Berrier, A. Tittl, and H. Giessen, “Large-Area Low-Cost Plasmonic Perfect Absorber Chemical Sensor Fabricated by Laser Interference Lithography,” ACS SENSORS, vol. 1, Art. no. 9, doi: 10.1021/acssensors.6b00444.

R. Takors and V. de Lorenzo, “Editorial overview: Microbial systems biology: systems biology prepares the ground for successful synthetic biology,” CURRENT OPINION IN MICROBIOLOGY, vol. 33, pp. VIII–X, doi: 10.1016/j.mib.2016.08.003.

J. Failmezger, R. Nitschel, A. Sanchez-Kopper, M. Kraml, and M. Siemann-Herzberg, “Site-Specific Cleavage of Ribosomal RNA in Escherichia coli-Based Cell-Free Protein Synthesis Systems,” PLoS One, vol. 11, Art. no. 12, doi: 10.1371/journal.pone.0168764.

A. Barth, S. Moreno-Bromberg, and O. Reichmann, “A Non-stationary Model of Dividend Distribution in a Stochastic Interest-Rate Setting,” COMPUTATIONAL ECONOMICS, vol. 47, Art. no. 3, doi: 10.1007/s10614-015-9502-y.

J. Bauknecht and G. Naegele, “Successful yet insufficient: German policies for higher employment rates among older age groups,” AUSTRALIAN JOURNAL OF SOCIAL ISSUES, vol. 51, Art. no. 2.

S. Aicher, Z. Christian, and M. Hirsch, “Rolling shear modulus and strength of beech wood laminations,” HOLZFORSCHUNG, vol. 70, Art. no. 8, doi: 10.1515/hf-2015-0229.

H. Bilgili, M. Buerger, C. Stubenrauch, and J. H. Porada, “About the nanostructure of the ternary system water - BMImPF6 - TX-100,” JOURNAL OF COLLOID AND INTERFACE SCIENCE, vol. 484, pp. 237–248, doi: 10.1016/j.jcis.2016.08.083.

M. Behrens et al., “Relationship between muscle volume and contractile properties of the human knee extensors,” APPLIED PHYSIOLOGY NUTRITION AND METABOLISM, vol. 41, Art. no. 1, doi: 10.1139/apnm-2015-0378.

M. Betie and S. Tenbohlen, “Power Transformer Diagnosis based on Mechanical Oscillations due to AC and DC Currents,” IEEE TRANSACTIONS ON DIELECTRICS AND ELECTRICAL INSULATION, vol. 23, Art. no. 3, SI, doi: 10.1109/TDEI.2016.005537.

A. Barth, R. Burger, I. Kroeker, and C. Rohde, “Computational uncertainty quantification for a clarifier-thickener model with several random perturbations: A hybrid stochastic Galerkin approach,” COMPUTERS & CHEMICAL ENGINEERING, vol. 89, pp. 11–26, doi: 10.1016/j.compchemeng.2016.02.016.

L. Junghans, A. Teleki, M. Becker, and R. Takors, “LC-MS-based compartment-specific metabolome analysis in CHO,” NEW BIOTECHNOLOGY, vol. 33, Art. no. S, doi: 10.1016/j.nbt.2016.06.842.

R. Z. Jurkowska and A. Jeltsch, “DNA Methyltransferases - Role and Function Preface,” in DNA METHYLTRANSFERASES - ROLE AND FUNCTION, vol. 945, Jeltsch, A and Jurkowska, RZ, Ed., in Advances in Experimental Medicine and Biology, vol. 945. , GEWERBESTRASSE 11, CHAM, CH-6330, SWITZERLAND: SPRINGER INT PUBLISHING AG, pp. V–VI.

B. Adhikari, G. Sivaraman, and M. Fyta, “Diamondoid-based molecular junctions: a computational study,” NANOTECHNOLOGY, vol. 27, Art. no. 48, doi: 10.1088/0957-4484/27/48/485207.

J. Wutz et al., “Predictability of k(L)a in stirred tank reactors under multiple operating conditions using an Euler-Lagrange approach,” ENGINEERING IN LIFE SCIENCES, vol. 16, Art. no. 7, doi: 10.1002/elsc.201500135.

L. D. Beju, D. P. Brindasu, N. C. Mutiu, and J. Rothmund, “Modeling, simulation and manufacturing of drill flutes,” INTERNATIONAL JOURNAL OF ADVANCED MANUFACTURING TECHNOLOGY, vol. 83, Art. no. 9–12, doi: 10.1007/s00170-015-7710-1.

G. Bellamy and U. Thiel, “Cuspidal Calogero-Moser and Lusztig families for Coxeter groups,” JOURNAL OF ALGEBRA, vol. 462, pp. 197–252, doi: 10.1016/j.jalgebra.2016.06.003.

V. Belser et al., “Aerodynamic and engineering design of a 1.5 s high quality microgravity drop tower facility,” ACTA ASTRONAUTICA, vol. 129, pp. 335–344, doi: 10.1016/j.actaastro.2016.09.031.

M. H. Beutel et al., “Microwave study of superconducting Sn films above and below percolation,” SUPERCONDUCTOR SCIENCE & TECHNOLOGY, vol. 29, Art. no. 8, doi: 10.1088/0953-2048/29/8/085011.

T. Bhandari, F. Hamad, C. Moormann, K. G. Sharma, and B. Westrich, “Numerical modelling of seismic slope failure using MPM,” COMPUTERS AND GEOTECHNICS, vol. 75, pp. 126–134, doi: 10.1016/j.compgeo.2016.01.017.

M. Akhlaghi, T. Steiner, S. R. Meka, and E. J. Mittemeijer, “Misfit-induced changes of lattice parameters in two-phase systems: coherent/incoherent precipitates in a matrix,” JOURNAL OF APPLIED CRYSTALLOGRAPHY, vol. 49, Art. no. 1, doi: 10.1107/S1600576715022608.

C.-M. Albrecht, S. Hattula, T. Bornemann, and W. D. Hoyer, “Customer response to interactional service experience The role of interaction environment,” JOURNAL OF SERVICE MANAGEMENT, vol. 27, Art. no. 5, doi: 10.1108/JOSM-07-2015-0215.

D. T. Banuti, V. Hannemann, K. Hannemann, and B. Weigand, “An efficient multi-fluid-mixing model for real gas reacting flows in liquid propellant rocket engines,” COMBUSTION AND FLAME, vol. 168, pp. 98–112, doi: 10.1016/j.combustflame.2016.03.029.

B. Alqarni, B. Colley, J. Klebensberger, D. McDougald, and S. A. Rice, “Expression stability of 13 housekeeping genes during carbon starvation of Pseudomonas aeruginosa,” JOURNAL OF MICROBIOLOGICAL METHODS, vol. 127, pp. 182–187, doi: 10.1016/j.mimet.2016.06.008.

A. Barth and F. G. Fuchs, “UNCERTAINTY QUANTIFICATION FOR HYPERBOLIC CONSERVATION LAWS WITH FLUX COEFFICIENTS GIVEN BY SPATIOTEMPORAL RANDOM FIELDS,” SIAM JOURNAL ON SCIENTIFIC COMPUTING, vol. 38, Art. no. 4, doi: 10.1137/15M1027723.

V. Avrutin, Z. T. Zhusubaliyev, and E. Mosekilde, “Border collisions inside the stability domain of a fixed point,” PHYSICA D-NONLINEAR PHENOMENA, vol. 321, pp. 1–15, doi: 10.1016/j.physd.2016.02.011.

M. Axtmann, R. Poser, J. von Wolfersdorf, and M. Bouchez, “Endwall heat transfer and pressure loss measurements in staggered arrays of adiabatic pin fins,” APPLIED THERMAL ENGINEERING, vol. 103, pp. 1048–1056, doi: 10.1016/j.applthermaleng.2016.04.066.

J. Pfizenmaier, L. Junghans, A. Teleki, and R. Takors, “Hyperosmotic stimulus study discloses benefits in ATP supply and reveals miRNA/mRNA targets to improve recombinant protein production of CHO cells,” BIOTECHNOLOGY JOURNAL, vol. 11, Art. no. 8, doi: 10.1002/biot.201500606.

R. Takors, “Editorial: How can we ensure the successful transfer from lab- to large-scale production?,” ENGINEERING IN LIFE SCIENCES, vol. 16, Art. no. 7, doi: 10.1002/elsc.201670073.

D. Beinke, C. Oberdorfer, and G. Schmitz, “Towards an accurate volume reconstruction in atom probe tomography,” ULTRAMICROSCOPY, vol. 165, pp. 34–41, doi: 10.1016/j.ultramic.2016.03.008.

F. Betancourt and C. Rohde, “Finite-volume schemes for Friedrichs systems with involutions,” APPLIED MATHEMATICS AND COMPUTATION, vol. 272, Art. no. 2, doi: 10.1016/j.amc.2015.03.050.

M. Aimer, E. Klemm, B. Langanke, H. Gehrke, and C. Stubenrauch, “Reactive Extraction of Lactic Acid by Using Tri-n-octylamine: Structure of the Ionic Phase,” CHEMISTRY-A EUROPEAN JOURNAL, vol. 22, Art. no. 10, doi: 10.1002/chem.201503799.

D. Barseghyan, P. Exner, H. Kovarik, and T. Weidl, “Semiclassical bounds in magnetic bottles,” REVIEWS IN MATHEMATICAL PHYSICS, vol. 28, Art. no. 1, doi: 10.1142/S0129055X16500021.

I. Amm, M. Kawan, and D. H. Wolf, “Characterization of protein quality control components via dual reporter-containing misfolded cytosolic model substrates,” ANALYTICAL BIOCHEMISTRY, vol. 515, pp. 14–21, doi: 10.1016/j.ab.2016.09.012.

A. D. Beck, D. G. Flad, C. Tonhaeuser, G. Gassner, and C.-D. Munz, “On the Influence of Polynomial De-aliasing on Subgrid Scale Models,” FLOW TURBULENCE AND COMBUSTION, vol. 97, Art. no. 2, doi: 10.1007/s10494-016-9704-y.

S. Becker, D. Schober, and S. Wassermann, “How to approach consumers’ nonmonetary evaluation of electricity supply security? The case of Germany from a multidisciplinary perspective,” UTILITIES POLICY, vol. 42, pp. 74–84, doi: 10.1016/j.jup.2016.06.012.

M. Loeffler, J. D. Simen, G. Jaeger, K. Schaeferhoff, A. Freund, and R. Takors, “Engineering E-coli for large-scale production - Strategies considering ATP expenses and transcriptional responses,” METABOLIC ENGINEERING, vol. 38, pp. 73–85, doi: 10.1016/j.ymben.2016.06.008.

C. Apprich, K. Hoellig, J. Hoerner, and U. Reif, “Collocation with WEB-Splines,” ADVANCES IN COMPUTATIONAL MATHEMATICS, vol. 42, Art. no. 4, doi: 10.1007/s10444-015-9444-x.

A. Berninger, “Thinking sadly: In favor of an adverbial theory of emotions,” PHILOSOPHICAL PSYCHOLOGY, vol. 29, Art. no. 6, doi: 10.1080/09515089.2016.1159294.

A. Bardossy and G. G. S. Pegram, “Space-time conditional disaggregation of precipitation at high resolution via simulation,” WATER RESOURCES RESEARCH, vol. 52, Art. no. 2, doi: 10.1002/2015WR018037.

A. Bardossy and S. Hoerning, “Gaussian and non-Gaussian inverse modeling of groundwater flow using copulas and random mixing,” WATER RESOURCES RESEARCH, vol. 52, Art. no. 6, doi: 10.1002/2014WR016820.

J. M. Bauer, W. Frey, and R. Peters, “Dual Palladium(II)/Tertiary Amine Catalysis for Asymmetric Regioselective Rearrangements of Allylic Carbamates,” CHEMISTRY-A EUROPEAN JOURNAL, vol. 22, Art. no. 16, doi: 10.1002/chem.201600138.

F. A. Bayer, M. Lorenzen, M. A. Mueller, and F. Allgoewer, “Robust economic Model Predictive Control using stochastic information,” AUTOMATICA, vol. 74, pp. 151–161, doi: 10.1016/j.automatica.2016.08.008.

M. Abbaszadeh, J. Kadkhodapour, S. Schmauder, and M. Hoseinpour, “A study on the effect of grain dimension on the deformation of stent struts in tension, bending and unbending loading modes,” INTERNATIONAL JOURNAL OF MECHANICAL SCIENCES, vol. 118, pp. 36–44, doi: 10.1016/j.ijmecsci.2016.09.010.

B. Acs, G. Szederkenyi, Z. Tuza, and Z. A. Tuza, “Computing all possible graph structures describing linearly conjugate realizations of kinetic systems,” COMPUTER PHYSICS COMMUNICATIONS, vol. 204, pp. 11–20, doi: 10.1016/j.cpc.2016.02.020.

T. Blascheck, M. John, K. Kurzhals, S. Koch, and T. Ertl, “VA(2): A Visual Analytics Approach for // Evaluating Visual Analytics Applications,” IEEE TRANSACTIONS ON VISUALIZATION AND COMPUTER GRAPHICS, vol. 22, Art. no. 1, doi: 10.1109/TVCG.2015.2467871.

A. Sanchez-Kopper, M. Becker, J. Pfizenmaier, C. Kessler, A. Karau, and R. Takors, “Tracking dipeptides at work-uptake and intracellular fate in CHO culture,” AMB EXPRESS, vol. 6, doi: 10.1186/s13568-016-0221-0.

S. Lieder, M. Jahn, J. Koepff, S. Mueller, and R. Takors, “Environmental stress speeds up DNA replication in Pseudomonas putida in chemostat cultivations,” BIOTECHNOLOGY JOURNAL, vol. 11, Art. no. 1, SI, doi: 10.1002/biot.201500059.

J. Rimbon, A. Sanchez-Kopper, A. Wahl, and R. Takors, “Monitoring intracellular protein degradation in antibody-producing Chinese hamster ovary cells,” ENGINEERING IN LIFE SCIENCES, vol. 15, Art. no. 5, SI, doi: 10.1002/elsc.201400103.

C. M. N. Mateo et al., “Enhanced efficiency of AlGaInP disk laser by in-well pumping,” OPTICS EXPRESS, vol. 23, Art. no. 3, doi: 10.1364/OE.23.002472.

P. Mucha, P. Berger, R. Weber, N. Speker, B. Sommer, and T. Graf, “Calibrated heat flow model for the determination of different heat-affected zones in single-pass laser-cut CFRP using a cw CO2 laser,” APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING, vol. 118, Art. no. 4, doi: 10.1007/s00339-014-8932-z.

A. Heider, R. Weber, D. Herrmann, P. Herzog, and T. Graf, “Power modulation to stabilize laser welding of copper,” JOURNAL OF LASER APPLICATIONS, vol. 27, Art. no. 2, doi: 10.2351/1.4906127.

M. Henkel et al., “Teaching bioprocess engineering to undergraduates: Multidisciplinary hands-on training in a one-week practical course,” BIOCHEMISTRY AND MOLECULAR BIOLOGY EDUCATION, vol. 43, Art. no. 3, doi: 10.1002/bmb.20860.

J. Pfizenmaier, J.-C. Matuszczyk, and R. Takors, “Changes in intracellular ATP-content of CHO cells as response to hyperosmolality,” BIOTECHNOLOGY PROGRESS, vol. 31, Art. no. 5, doi: 10.1002/btpr.2143.

C. Freitag et al., “High-quality processing of CFRP with a 1.1-kW picosecond laser,” APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING, vol. 119, Art. no. 4, doi: 10.1007/s00339-015-9159-3.

A. Teleki, A. Sanchez-Kopper, and R. Takors, “Alkaline conditions in hydrophilic interaction liquid chromatography for intracellular metabolite quantification using tandem mass spectrometry,” ANALYTICAL BIOCHEMISTRY, vol. 475, pp. 4–13, doi: 10.1016/j.ab.2015.01.002.

T. Vallon et al., “Applying systems biology tools to study n-butanol degradation in Pseudomonas putida KT2440,” ENGINEERING IN LIFE SCIENCES, vol. 15, Art. no. 8, doi: 10.1002/elsc.201400051.

E. Caracciolo et al., “Single-grating-mirror intracavity stretcher design for chirped pulse regenerative amplification,” OPTICS LETTERS, vol. 40, Art. no. 7, doi: 10.1364/OL.40.001532.

S. Sudarsan, S. Dethlefsen, L. M. Blank, M. Siemann-Herzberg, and A. Schmid, “The Functional Structure of Central Carbon Metabolism in Pseudomonas putida KT2440,” APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 80, Art. no. 17, doi: 10.1128/AEM.01643-14.

R. Lindner, A. Moosmann, A. Dietrich, H. Boettinger, R. Kontermann, and M. Siemann-Herzberg, “Process development of periplasmatically produced single chain fragment variable against epidermal growth factor receptor in Escherichia coli,” JOURNAL OF BIOTECHNOLOGY, vol. 192, Art. no. A, doi: 10.1016/j.jbiotec.2014.10.003.

J. Buchholz, M. Graf, B. Blombach, and R. Takors, “Improving the carbon balance of fermentations by total carbon analyses,” BIOCHEMICAL ENGINEERING JOURNAL, vol. 90, pp. 162–169, doi: 10.1016/j.bej.2014.06.007.

R. Gelves, A. Dietrich, and R. Takors, “Modeling of gas-liquid mass transfer in a stirred tank bioreactor agitated by a Rushton turbine or a new pitched blade impeller,” BIOPROCESS AND BIOSYSTEMS ENGINEERING, vol. 37, Art. no. 3, doi: 10.1007/s00449-013-1001-8.

S. Lieder, M. Jahn, J. Seifert, M. von Bergen, S. Mueller, and R. Takors, “Subpopulation-proteomics reveal growth rate, but not cell cycling, as a major impact on protein composition in Pseudomonas putida KT2440,” AMB EXPRESS, vol. 4, doi: 10.1186/s13568-014-0071-6.

T. Schuhmacher, M. Loeffler, T. Hurler, and R. Takors, “Phosphate limited fed-batch processes: Impact on carbon usage and energy metabolism in Escherichia coli,” JOURNAL OF BIOTECHNOLOGY, vol. 190, pp. 96–104, doi: 10.1016/j.jbiotec.2014.04.025.

R. Weber et al., “Heat accumulation during pulsed laser materials processing (vol 22, pg 11312, 2014),” OPTICS EXPRESS, vol. 22, Art. no. 23, doi: 10.1364/OE.22.028232.

T. Vallon et al., “Production of 1-Octanol from n-Octane by Pseudomonas putida KT2440,” CHEMIE INGENIEUR TECHNIK, vol. 85, Art. no. 6, doi: 10.1002/cite.201200178.

S. Soellner, M. Rahnert, M. Siemann-Herzberg, R. Takors, and J. Altenbuchner, “Evolution of pyruvate kinase-deficient Escherichia coli mutants enables glycerol-based cell growth and succinate production,” JOURNAL OF APPLIED MICROBIOLOGY, vol. 115, Art. no. 6, doi: 10.1111/jam.12333.

J. Bongaerts et al., “Diversity-Oriented Production of Metabolites Derived from Chorismate and Their Use in Organic Synthesis,” ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 50, Art. no. 34, doi: 10.1002/anie.201103261.

O. Vielhauer, M. Zakhartsev, T. Horn, R. Takors, and M. Reuss, “Simplified absolute metabolite quantification by gas chromatography-isotope dilution mass spectrometry on the basis of commercially available source material,” JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, vol. 879, Art. no. 32, doi: 10.1016/j.jchromb.2011.10.036.

M. Wenzel, A. Mueller, M. Siemann-Herzberg, and J. Altenbuchner, “Self-Inducible Bacillus subtilis Expression System for Reliable and Inexpensive Protein Production by High-Cell-Density Fermentation,” APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 77, Art. no. 18, doi: 10.1128/AEM.05219-11.

T. Schuhmacher, K. Lemuth, T. Hardiman, G. Vacun, M. Reuss, and M. Siemann-Herzberg, “Quantifying cytosolic messenger RNA concentrations in Escherichia coli using real-time polymerase chain reaction for a systems biology approach,” ANALYTICAL BIOCHEMISTRY, vol. 398, Art. no. 2, doi: 10.1016/j.ab.2009.11.025.

A. B. Canelas et al., “Integrated multilaboratory systems biology reveals differences in protein metabolism between two reference yeast strains,” NATURE COMMUNICATIONS, vol. 1, doi: 10.1038/ncomms1150.

T. Hardiman, H. Meinhold, J. Hofmann, J. C. Ewald, M. Siemann-Herzberg, and M. Reuss, “Prediction of kinetic parameters from DNA-binding site sequences for modeling global transcription dynamics in Escherichia coli,” METABOLIC ENGINEERING, vol. 12, Art. no. 3, doi: 10.1016/j.ymben.2009.10.006.

J. B. Magnus, M. Oldiges, and R. Takors, “The Identification of Enzyme Targets for the Optimization of a Valine Producing Corynebacterium glutamicum Strain Using a Kinetic Model,” BIOTECHNOLOGY PROGRESS, vol. 25, Art. no. 3, doi: 10.1002/btpr.184.

K. Lemuth et al., “Global Transcription and Metabolic Flux Analysis of Escherichia coli in Glucose-Limited Fed-Batch Cultivations,” APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 74, Art. no. 22, doi: 10.1128/AEM.01327-08.

T. Hardiman et al., “In vitro synthesis and characterization of guanosine 3 `,5 `-bis(diphosphate),” ANALYTICAL BIOCHEMISTRY, vol. 383, Art. no. 2, doi: 10.1016/j.ab.2008.07.042.

R. Takors, B. Bathe, M. Rieping, S. Hans, R. Kelle, and K. Huthmacher, “Systems biology for industrial strains and fermentation processes - Example: Amino acids,” JOURNAL OF BIOTECHNOLOGY, vol. 129, Art. no. 2, doi: 10.1016/j.jbiotec.2007.01.031.

T. Hardiman, K. Lemuth, M. A. Keller, M. Reuss, and M. Siemann-Herzberg, “Topology of the global regulatory network of carbon limitation in Escherichia coli,” JOURNAL OF BIOTECHNOLOGY, vol. 132, Art. no. 4, doi: 10.1016/j.jbiotec.2007.08.029.

K. Noeh, K. Groenke, B. Luo, R. Takors, M. Oldiges, and W. Wiechert, “Metabolic flux analysis at ultra short time scale: Isotopically non-stationary C-13 labeling experiments,” JOURNAL OF BIOTECHNOLOGY, vol. 129, Art. no. 2, doi: 10.1016/j.jbiotec.2006.11.015.

S. Wahl, R. Takors, and W. Wiechert, “Interpretation of metabolic flux maps by limitation potentials and constrained limitation sensitivities,” BIOTECHNOLOGY AND BIOENGINEERING, vol. 94, Art. no. 2, doi: 10.1002/bit.20837.

M. Franzreb, M. Siemann-Herzberg, T. Hobley, and O. Thomas, “Protein purification using magnetic adsorbent particles,” APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, vol. 70, Art. no. 5, doi: 10.1007/s00253-006-0344-3.

M. Franzreb et al., “Direct bioproduct isolation from crude feedstocks using magnetic micro adsorbents,” JOURNAL OF BIOTECHNOLOGY, vol. 118, Art. no. 1.

M. Oldiges and R. Takors, “Applying metabolic profiling techniques for stimulus-response experiments: Chances and pitfalls,” in TECHNOLOGY TRANSFER IN BIOTECHNOLOGY: FROM LAB TO INDUSTRY TO PRODUCTION, vol. 92, in Advances in Biochemical Engineering-Biotechnology, vol. 92. , HEIDELBERGER PLATZ 3, D-14197 BERLIN, GERMANY: SPRINGER-VERLAG BERLIN, pp. 173–196. doi: 10.1007/b98913.